Organic Reactions: Master the Fundamentals with Interactive Quizzes

Question 1

In a nucleophilic substitution reaction, the nucleophile is characterized by:

Accepted Answer

Being an electron-rich species

Answer

Having a positive charge

Answer

Being a weak base

Answer

Following a concerted reaction mechanism

Question 2

During an electrophilic addition reaction, the electrophile is:

Accepted Answer

An electron-deficient species

Answer

A nucleophile

Answer

A leaving group

Answer

A catalyst

Question 3

Which of the following is a key characteristic of concerted reactions?

Accepted Answer

They occur in a single step

Answer

Reactants and products are in equilibrium

Answer

The reaction rate is first-order in each reactant

Answer

They proceed through an intermediate

Question 4

Which of the following reactions is an example of an elimination reaction?

Accepted Answer

CH3CH2CH2Br + NaOH → CH3CH=CH2 + NaBr + H2O

Answer

CH3CH2OH + HBr → CH3CH2Br + H2O

Answer

CH3CH2CH2Cl + Mg → CH3CH=CH2 + MgCl2

Answer

CH3COOH + NaOH → CH3COONa + H2O

Question 5

The reaction rate of a nucleophilic substitution reaction is primarily influenced by the:

Accepted Answer

Concentrations of both the nucleophile and substrate

Answer

Nucleophile concentration only

Answer

Substrate concentration only

Answer

Neither the nucleophile nor the substrate concentration

Question 6

Which reagent is most suitable for carrying out an E1 elimination reaction?

Accepted Answer

Sulfuric acid (H2SO4)

Answer

Sodium hydroxide (NaOH)

Answer

Potassium hydroxide (KOH)

Answer

Sodium methoxide (NaOCH3)

Question 7

In an E2 elimination reaction, the base abstracts:

Accepted Answer

A proton from a carbon adjacent to the leaving group

Answer

A proton from the carbon bearing the leaving group

Answer

An electron from the carbon adjacent to the leaving group

Answer

An electron from the carbon bearing the leaving group

Question 8

Which of the following reagents is used to perform an E1 elimination reaction?

Accepted Answer

H2SO4

Answer

NaOH

Answer

KOH

Answer

CH3COOH

Question 9

Identify the most effective reagent for promoting an E2 elimination reaction.

Accepted Answer

Strong base

Answer

Strong acid

Answer

Weak acid

Answer

Weak base

Question 10

Which characteristic is associated with a concerted reaction?

Accepted Answer

Single-step occurrence

Answer

High activation energy

Answer

Formation of a carbocation intermediate

Answer

Favorability in polar solvents

Question 11

Which characteristic is associated with an SN1 reaction?

Accepted Answer

Unimolecular

Answer

Bimolecular

Answer

Concerted

Answer

Stepwise

Question 12

Which of the following is a characteristic of nucleophilic substitution reactions?

Accepted Answer

Nucleophile attacks an electrophile

Answer

Electrophile attacks a nucleophile

Question 13

Which of the following compounds is most likely to undergo electrophilic addition?

Accepted Answer

Ethene

Answer

Ethane

Answer

Acetylene

Answer

Propane

Question 14

What type of reaction occurs when an alcohol reacts with a strong base?

Accepted Answer

Elimination

Answer

Nucleophilic substitution

Answer

Electrophilic addition

Answer

Oxidation

Question 15

Which of the following reagents is used to perform a nucleophilic addition reaction?

Accepted Answer

NH3

Answer

HBr

Answer

KMnO4

Answer

H2SO4

Question 16

What is the rate-determining step in an E1 elimination reaction?

Accepted Answer

Formation of the carbocation

Answer

Removal of the proton

Answer

Formation of the double bond

Answer

Attack of the base

Question 17

What is the hybridization of the carbon atom in the product of an electrophilic addition reaction?

Accepted Answer

sp3

Answer

sp

Answer

sp2

Answer

sp3d

Question 18

Which of the following reagents is commonly used to carry out a nucleophilic substitution reaction?

Accepted Answer

Sodium hydroxide (NaOH)

Answer

Sulfuric acid (H2SO4)

Answer

Potassium permanganate (KMnO4)

Answer

Sodium borohydride (NaBH4)

Question 19

What is the fundamental mechanism of the substitution nucleophilic unimolecular (SN1) reaction?

Accepted Answer

Nucleophilic attack on a carbocation intermediate

Answer

Direct nucleophilic substitution on a substrate

Answer

Electrophilic addition followed by proton abstraction

Answer

Base-promoted elimination followed by nucleophilic addition

Question 20

Which type of organic reaction involves the breaking of a carbon-carbon bond?

Accepted Answer

Elimination

Answer

Substitution

Answer

Addition

Answer

Rearrangement

Question 21

What is the hybridization of the carbon atom in a carbonyl group (C=O)?

Accepted Answer

sp2

Answer

sp

Answer

sp3

Answer

sp3d

Question 22

Which of the following is NOT a type of nucleophilic substitution reaction?

Accepted Answer

E1

Answer

SN1

Answer

SN2

Question 23

Which of the following is the major product of the following reaction?
CH3CH=CH2 + HBr ---->

Accepted Answer

CH3CHBrCH3

Answer

CH3CH2CH2Br

Question 24

Which of the following is the rate-determining step in an SN1 reaction?

Accepted Answer

Formation of the carbocation

Answer

Attack of the nucleophile on the carbocation

Question 25

Which of the following is the strongest nucleophile?

Accepted Answer

OH-

Answer

NH3

Question 26

Which of the following is the hybridization of the carbon atom in the product of an SN2 reaction?

Accepted Answer

sp3

Answer

sp2

Question 27

In a nucleophilic substitution reaction, which species attacks the electrophile?

Accepted Answer

Nucleophile

Answer

Electrophile

Answer

Free radical

Answer

Carbocation

Question 28

Identify the type of reaction in which a nucleophile attacks the electrophile:

Accepted Answer

Nucleophilic substitution

Answer

Electrophilic addition

Answer

Elimination

Answer

Electrophilic aromatic substitution

Question 29

Which of the following is the weakest leaving group in nucleophilic substitution reactions?

Accepted Answer

Fluoride

Answer

Iodide

Answer

Bromide

Answer

Chloride

Question 30

What is the hybridization of the carbon atom in the product of the hydrogenation reaction: CH3CH=CH2 + H2 →

Accepted Answer

sp3

Answer

sp

Answer

sp2

Answer

sp3d

Question 31

Which of the following mechanisms accurately describes the nucleophilic substitution reaction between a primary alkyl halide and a hydroxide ion? Is it?

Accepted Answer

SN2

Answer

SN1

Answer

E1

Answer

E2

Question 32

In the reaction CH2=CH2 + HBr, which species functions as the electrophile?

Accepted Answer

HBr

Answer

CH2=CH2

Answer

Br-

Answer

H+

Question 33

In the reaction cis-2-butene + HBr, what is the stereochemistry of the product formed?

Accepted Answer

trans-2-bromobutane

Answer

cis-2-bromobutane

Answer

1-bromobutane

Answer

2-bromobutene

Question 34

According to IUPAC nomenclature, what is the correct name for the compound CH3CH(OH)CH2CH3?

Accepted Answer

butan-2-ol

Answer

2-butanol

Answer

1-hydroxybutane

Answer

4-hydroxybutane