Tuberculosis Learning Quizzes: Pathophysiology, Diagnosis, and Management

Question 1

Which of the following is a hallmark clinical manifestation of active tuberculosis (TB) infection?

Accepted Answer

Persistent cough with sputum production

Answer

Asymptomatic presentation

Answer

Isolated skin rash without other symptoms

Answer

Neurological symptoms without pulmonary involvement

Question 2

Which of the following is a typical clinical manifestation of pulmonary tuberculosis?

Accepted Answer

Productive cough

Accepted Answer

Hemoptysis

Answer

Axillary lymphadenopathy

Answer

Parotitis

Question 3

In selecting anti-tubercular medications, which factor is paramount?

Accepted Answer

Drug resistance patterns

Answer

Patient's age

Answer

Patient's weight

Question 4

How does Mycobacterium tuberculosis primarily establish an active infection in humans?

Accepted Answer

Inhalation of respiratory droplets containing the bacteria

Answer

Direct contact with infected skin or mucous membranes

Answer

Ingestion of contaminated food or water

Answer

Through the bite of an infected insect vector

Question 5

In determining the duration of anti-tubercular therapy, which factor holds the greatest influence?

Accepted Answer

Drug susceptibility of the organism

Answer

Severity of the infection

Answer

Patient's age and weight

Answer

Patient's compliance with treatment

Question 6

Which of the following is the most common clinical presentation of tuberculous meningitis?

Accepted Answer

Headache, stiff neck, nausea, and vomiting

Answer

Cough, hemoptysis, fever, and weight loss

Answer

Diarrhea, abdominal pain, and fever

Answer

Skin lesions, lymphadenopathy, and fever

Question 7

In pulmonary tuberculosis, which factor is paramount in ensuring successful treatment outcomes?

Accepted Answer

Patient adherence to anti-tubercular therapy

Answer

Early detection of the infection

Answer

Appropriate antibiotic selection

Answer

Adequate nutritional support

Question 8

The causative agent of tuberculosis is:

Accepted Answer

Mycobacterium tuberculosis

Answer

Staphylococcus aureus

Answer

Streptococcus pneumoniae

Answer

Haemophilus influenzae

Question 9

The most prevalent site of tuberculosis infection is the:

Accepted Answer

Lungs

Answer

Meninges

Answer

Lymph nodes

Answer

Bones

Question 10

Identify the characteristic clinical manifestation of pulmonary tuberculosis:

Accepted Answer

Persistent cough

Answer

Parotitis

Answer

Skin lesions

Answer

Hepatomegaly

Question 11

For diagnosing tuberculosis, which test is considered the gold standard?

Accepted Answer

Acid-fast bacillus (AFB) smear and culture

Answer

Tuberculin skin test

Answer

Chest X-ray

Answer

Sputum Gram stain

Question 12

Which antibiotic combination is the first-line regimen for treating drug-susceptible tuberculosis?

Accepted Answer

Isoniazid, rifampin, pyrazinamide, and ethambutol

Answer

Clarithromycin, azithromycin, erythromycin

Answer

Ciprofloxacin, levofloxacin, moxifloxacin

Answer

Amoxicillin, clavulanate, cefuroxime

Question 13

What is the recommended duration of treatment for drug-susceptible tuberculosis?

Accepted Answer

6 months

Answer

3 months

Answer

18 months

Answer

12 months

Question 14

Identify the primary mode of transmission for tuberculosis:

Accepted Answer

Inhalation of airborne droplets

Answer

Direct skin contact

Answer

Contact with infected blood or body fluids

Answer

Ingestion of contaminated food or water

Question 15

Which of the following is **NOT** a common clinical manifestation of **pulmonary** tuberculosis?

Accepted Answer

Diarrhea

Answer

Hemoptysis

Answer

Cough

Answer

Weight loss

Question 16

What is the primary **sputum**-based diagnostic test for **active** tuberculosis?

Accepted Answer

Sputum smear microscopy

Answer

Blood culture

Answer

Chest X-ray

Answer

Tuberculin skin test

Question 17

Which of the following antibiotics is **NOT** included in the **initial** regimen for treating **drug-susceptible** tuberculosis?

Accepted Answer

Streptomycin

Answer

Ethambutol

Answer

Rifampin

Answer

Isoniazid

Question 18

Which of the following is a risk factor for the development of **latent** tuberculosis infection?

Accepted Answer

Close contact with an infected individual

Answer

Obesity

Answer

Smoking

Answer

Alcohol abuse

Question 19

What is the name of the bacterium that causes **all forms of** tuberculosis?

Accepted Answer

Mycobacterium tuberculosis

Answer

Streptococcus pneumoniae

Answer

Haemophilus influenzae

Answer

Staphylococcus aureus

Question 20

What is the recommended treatment regimen for patients with **new** drug-resistant tuberculosis, including multidrug-resistant tuberculosis (MDR-TB)?

Accepted Answer

Multidrug-resistant tuberculosis (MDR-TB) regimen

Answer

Second-line antituberculosis regimen

Answer

First-line antituberculosis regimen

Answer

Extensively drug-resistant tuberculosis (XDR-TB) regimen

Question 21

What is the primary causative agent of tuberculosis?

Accepted Answer

Mycobacterium tuberculosis

Answer

Streptococcus pneumoniae

Answer

Staphylococcus aureus

Answer

Haemophilus influenzae

Question 22

Which of the following anatomical structures is the primary site of infection in tuberculosis?

Accepted Answer

Lungs

Answer

Lymph nodes

Answer

Gastrointestinal tract

Answer

Skin

Question 23

Which of the following is a common clinical manifestation of tuberculosis?

Accepted Answer

Persistent, productive cough

Answer

Rash

Answer

Diarrhea

Question 24

Which of the following medications is commonly used as first-line therapy for uncomplicated tuberculosis?

Accepted Answer

Isoniazid

Answer

Amoxicillin

Answer

Ciprofloxacin

Answer

Metronidazole

Question 25

What is the recommended duration of treatment for uncomplicated, drug-susceptible tuberculosis?

Accepted Answer

6 months

Answer

9 months

Answer

12 months

Answer

3 months

Question 26

What is the most common method of transmission of tuberculosis?

Accepted Answer

Inhalation

Answer

Contact

Answer

Ingestion

Question 27

What is a primary role of the nurse in the management of tuberculosis?

Accepted Answer

Patient education and support

Answer

Ordering diagnostic tests

Answer

Prescribing medications

Answer

Performing surgery

Question 28

Which of the following is a well-established risk factor for the development of tuberculosis (TB)?

Accepted Answer

HIV infection

Answer

Absence of substance abuse

Answer

Recent travel to a region with low incidence of TB

Answer

Good nutrition

Question 29

Which of the following clinical manifestations is most commonly associated with pulmonary tuberculosis?

Accepted Answer

Chronic cough

Answer

Neurological symptoms

Answer

Skin rash

Question 30

Which diagnostic test is considered the reference standard for diagnosing active TB?

Accepted Answer

Sputum culture

Answer

Interferon-gamma release assay (IGRA)

Answer

Tuberculin skin test (TST)

Answer

Chest X-ray

Question 31

Which of the following drugs is included in the recommended first-line regimen for treating drug-sensitive TB?

Accepted Answer

Isoniazid

Answer

Rifabutin

Answer

Ethionamide

Answer

Streptomycin

Question 32

Which of the following adverse effects is commonly associated with the use of isoniazid in TB treatment?

Accepted Answer

Hepatotoxicity

Answer

Neurotoxicity

Answer

Nephrotoxicity

Answer

Cardiotoxicity

Question 33

What is the primary objective of the directly observed therapy (DOT) approach in TB management?

Accepted Answer

To ensure adherence to treatment and prevent the development of drug resistance

Answer

To provide emotional support to patients

Answer

To reduce stigma associated with TB

Question 34

Which of the following is NOT a recommended infection control practice for preventing the transmission of TB?

Accepted Answer

Allowing patients with active TB to visit public places without wearing a face mask

Answer

Using airborne infection isolation rooms

Answer

Educating patients about proper cough etiquette

Answer

Providing respiratory protection to healthcare workers

Question 35

What is the ultimate goal of the World Health Organization's End TB Strategy?

Accepted Answer

To end the global TB epidemic as a public health threat by 2035

Answer

To strengthen health systems in low- and middle-income countries

Answer

To reduce TB mortality by 50% by 2025

Answer

To develop a universal vaccine against TB

Question 36

What is a key principle of the patient-centered approach to TB care?

Accepted Answer

Involving patients in decision-making and providing personalized treatment plans

Answer

Prioritizing treatment completion rates over patient satisfaction

Answer

Administering standardized treatment protocols to all patients

Question 37

The causative agent of tuberculosis is:

Accepted Answer

Mycobacterium tuberculosis

Answer

Haemophilus influenzae

Answer

Streptococcus pneumoniae

Answer

Staphylococcus aureus

Question 38

The definitive diagnostic test for tuberculosis is:

Accepted Answer

Sputum culture

Answer

Interferon-gamma release assay

Answer

Tuberculin skin test

Answer

Chest X-ray

Question 39

A first-line drug used in the treatment of tuberculosis is:

Accepted Answer

Isoniazid

Answer

Vancomycin

Answer

Azithromycin

Answer

Fluconazole

Question 40

A potential adverse effect of isoniazid is:

Accepted Answer

Hepatotoxicity

Answer

Cardiotoxicity

Answer

Nephrotoxicity

Answer

Ototoxicity

Question 41

Tuberculosis is primarily transmitted through:

Accepted Answer

Inhalation of airborne droplets

Answer

Ingestion of contaminated food

Answer

Vector-borne transmission

Answer

Contact with infected blood

Question 42

A patient factor that increases the risk of developing active tuberculosis is:

Accepted Answer

Immunosuppression

Answer

Female gender

Answer

Good nutrition

Answer

Young age

Question 43

The vaccine used to prevent tuberculosis is:

Accepted Answer

Bacillus Calmette-Guérin (BCG)

Answer

Measles vaccine

Answer

Polio vaccine

Answer

Hepatitis B vaccine

Question 44

A crucial nursing intervention in the management of tuberculosis is:

Accepted Answer

Patient education and adherence monitoring

Answer

Intravenous fluid administration

Answer

Wound care

Answer

Ventilator management