Peptic Ulcer Disease: Causes, Symptoms, and Treatment

Question 1

Which of the following mechanisms helps protect the gastric mucosa against peptic ulcer disease?

Accepted Answer

Prostaglandin synthesis

Answer

Increased mucosal blood flow

Answer

Gastric acid secretion

Answer

Pepsin secretion

Question 2

Which of the following is NOT a common symptom of peptic ulcer disease?

Accepted Answer

Frequent bowel movements (constipation)

Answer

Burning sensation in the upper abdomen (epigastric pain)

Answer

Heartburn

Answer

Nausea

Question 3

Which diagnostic technique provides the most accurate visualization of a peptic ulcer?

Accepted Answer

Upper endoscopy

Answer

Barium swallow

Answer

Capsule endoscopy

Answer

Magnetic resonance imaging (MRI)

Question 4

Which of the following is a commonly used proton pump inhibitor (PPI) for treating peptic ulcer disease?

Accepted Answer

Omeprazole

Answer

Ranitidine

Answer

Metoclopramide

Answer

Sucralfate

Question 5

Which medication is used to neutralize stomach acid and protect the gastric lining in the treatment of peptic ulcer disease?

Accepted Answer

Sucralfate

Answer

Misoprostol

Answer

Metoclopramide

Answer

Ondansetron

Question 6

Which of the following medications is a proton pump inhibitor commonly used in treating peptic ulcer disease?

Accepted Answer

Omeprazole

Answer

Cimetidine

Answer

Ranitidine

Answer

Sucralfate

Question 7

Which of the following is NOT a goal of pharmacological therapy for peptic ulcer disease?

Accepted Answer

To eradicate the infection

Answer

To reduce gastric acid secretion

Answer

To promote ulcer healing

Answer

To prevent complications

Question 8

When selecting a pharmacological treatment for peptic ulcer disease, which of the following factors is most important to consider?

Accepted Answer

The severity of the disease

Answer

The patient's age

Answer

The patient's medication history

Answer

The cost of the medication

Question 9

Which of the following is the most common identifiable cause of peptic ulcer disease?

Accepted Answer

Helicobacter pylori infection

Answer

Nonsteroidal anti-inflammatory drugs (NSAIDs)

Answer

Zollinger-Ellison syndrome

Answer

Excessive alcohol consumption

Question 10

What is the most common initial symptom reported by patients with peptic ulcer disease?

Accepted Answer

Epigastric pain

Answer

Dysphagia

Answer

Hematemesis

Answer

Melena

Question 11

Which diagnostic test provides the most definitive confirmation of the presence of a peptic ulcer?

Accepted Answer

Upper endoscopy

Answer

Barium swallow

Answer

Computed tomography (CT) scan

Answer

Magnetic resonance imaging (MRI)

Question 12

What is the primary mechanism of action of proton pump inhibitors (PPIs) in treating peptic ulcer disease?

Accepted Answer

Inhibiting gastric acid secretion

Answer

Neutralizing gastric acid

Answer

Promoting mucosal healing

Answer

Reducing gastric motility

Question 13

What is the generally recommended duration of therapy with proton pump inhibitors (PPIs) for the treatment of peptic ulcer disease caused by Helicobacter pylori?

Accepted Answer

8-12 weeks

Answer

4-8 weeks

Answer

12-16 weeks

Answer

16-20 weeks

Question 14

Which diagnostic test for peptic ulcer disease provides both high sensitivity (90-100%) and specificity (80-95%)?

Accepted Answer

Upper endoscopy

Answer

Stool antigen test

Answer

Barium swallow

Answer

Breath test

Question 15

Which diagnostic procedure is considered the gold standard for the definitive diagnosis of peptic ulcer disease?

Accepted Answer

Upper gastrointestinal (GI) endoscopy

Answer

Barium swallow radiography

Answer

Computed tomography (CT) scan

Answer

Magnetic resonance imaging (MRI)

Question 16

Among the following medications, which is a proton pump inhibitor commonly used in the treatment of peptic ulcer disease?

Accepted Answer

Omeprazole

Answer

Ranitidine

Answer

Sucralfate

Answer

Bismuth subsalicylate

Question 17

For patients with peptic ulcer disease, which drug combination is the primary treatment to eliminate H. pylori infection?

Accepted Answer

Triple therapy: proton pump inhibitor, amoxicillin, and clarithromycin

Answer

Proton pump inhibitor alone

Answer

Quadruple therapy: proton pump inhibitor, bismuth, metronidazole, and tetracycline

Answer

Histamine-2 receptor antagonist alone

Question 18

Which of the following is the primary cause of peptic ulcers?

Accepted Answer

Helicobacter pylori infection

Answer

Aspirin use

Answer

Stress

Answer

Excessive alcohol consumption

Question 19

Which of the following is a typical clinical manifestation of peptic ulcer disease?

Accepted Answer

Epigastric pain that is relieved by food

Answer

Constipation

Answer

Diarrhea

Answer

Vomiting

Question 20

Which of the following diagnostic procedures is considered the gold standard for diagnosing peptic ulcer disease?

Accepted Answer

Upper endoscopy

Answer

Blood test

Answer

X-ray imaging

Answer

Biopsy

Question 21

Which of the following lifestyle modifications is recommended for patients with peptic ulcer disease?

Accepted Answer

Smoking cessation

Answer

Increased alcohol intake

Answer

High-fat diet

Answer

Caffeine consumption

Question 22

Which of the following complications is a potential consequence of untreated peptic ulcer disease?

Accepted Answer

Hemorrhage

Answer

Renal failure

Answer

Sepsis

Answer

Pneumonia

Question 23

Which of the following patient populations is at increased risk of developing peptic ulcer disease?

Accepted Answer

Elderly patients

Answer

Healthy adults

Answer

Pregnant women

Answer

Children

Question 24

Which of the following dietary factors can help prevent the development of peptic ulcer disease?

Accepted Answer

Fruits and vegetables

Answer

Red meat

Answer

Spicy foods

Answer

Processed foods

Question 25

Which of the following nursing interventions is appropriate for a patient with peptic ulcer disease?

Accepted Answer

Promoting stress reduction

Answer

Restricting fluids

Answer

Encouraging smoking

Question 26

Which of the following is the most common clinical manifestation of peptic ulcer disease?

Accepted Answer

Epigastric pain

Answer

Melena

Answer

Hematemesis

Answer

Perforation

Question 27

Which diagnostic test is most commonly used to confirm the diagnosis of peptic ulcer disease?

Accepted Answer

Upper endoscopy

Answer

Helicobacter pylori breath test

Answer

Stool occult blood test

Answer

Barium swallow

Question 28

Which of the following medications is a proton pump inhibitor?

Accepted Answer

Omeprazole

Answer

Misoprostol

Answer

Ranitidine

Answer

Sucralfate

Question 29

Which of the following is a potential complication of peptic ulcer disease?

Accepted Answer

Perforation

Answer

Appendicitis

Answer

Pneumonia

Answer

Cholecystitis

Question 30

Which of the following laboratory findings is consistent with peptic ulcer disease?

Accepted Answer

Positive Hemoccult

Answer

Increased serum gastrin level

Answer

Elevated white blood cell count

Answer

Positive pregnancy test

Question 31

The primary etiologic agent for most cases of peptic ulcer disease is:

Accepted Answer

Helicobacter pylori

Answer

Clostridium difficile

Answer

Staphylococcus aureus

Answer

Escherichia coli

Question 32

Which of the following is a well-established risk factor for peptic ulcer disease?

Accepted Answer

Nonsteroidal anti-inflammatory drug (NSAID) use

Answer

Diet high in fruits and vegetables

Answer

Routine exercise

Question 33

The most common clinical manifestation of peptic ulcer disease is:

Accepted Answer

Epigastric pain

Answer

Nausea

Answer

Constipation

Answer

Vomiting

Question 34

Which diagnostic test is considered the gold standard for confirming a diagnosis of peptic ulcer disease?

Accepted Answer

Upper endoscopy

Answer

Ultrasound

Answer

Abdominal X-ray

Answer

Blood test

Question 35

The initial pharmacological treatment for peptic ulcer disease caused by Helicobacter pylori infection typically involves:

Accepted Answer

Triple therapy (proton pump inhibitor, amoxicillin, and clarithromycin)

Answer

Metoclopramide

Answer

Sucralfate

Question 36

Which of the following medications is commonly used to prevent NSAID-induced peptic ulcer disease?

Accepted Answer

Misoprostol

Answer

Ibuprofen

Answer

Aspirin

Answer

Acetaminophen

Question 37

For a patient with peptic ulcer disease experiencing acute epigastric pain, the most appropriate nursing intervention is to:

Accepted Answer

Administer an antacid

Answer

Encourage the patient to eat a bland diet

Answer

Prescribe antibiotics

Answer

Refer the patient for immediate surgery

Question 38

A potential complication of peptic ulcer disease is:

Accepted Answer

Perforation

Answer

Heart failure

Answer

Colon cancer

Answer

Stroke

Question 39

Patient education for peptic ulcer disease should emphasize:

Accepted Answer

Lifestyle modifications, medication adherence, and warning signs of complications

Answer

Pharmacological management only

Answer

Dietary restrictions only

Question 40

Which of the following lifestyle modifications is recommended for patients with peptic ulcer disease?

Accepted Answer

Avoiding smoking and alcohol consumption

Answer

Increasing caffeine intake

Answer

Eating spicy foods

Answer

Consuming large meals