Glycolysis: The Process of Glucose Breakdown - Interactive Learning Quiz

Question 1

Which of the following accurately represents the initial step of glycolysis?

Accepted Answer

Phosphorylation of glucose

Answer

Splitting of fructose-1,6-bisphosphate

Answer

Conversion of pyruvate to lactate

Answer

Generation of acetyl-CoA

Question 2

What is the net yield of ATP molecules produced during glycolysis?

Accepted Answer

4

Answer

0

Answer

2

Answer

6

Question 3

Which enzyme is responsible for catalyzing the conversion of glucose-6-phosphate to fructose-6-phosphate?

Accepted Answer

Glucose-6-phosphate isomerase

Answer

Hexokinase

Answer

Phosphofructokinase

Answer

Aldolase

Question 4

What is the primary function of NAD+ in glycolysis?

Accepted Answer

Electron acceptor

Answer

Substrate for pyruvate kinase

Answer

Cofactor for hexokinase

Answer

Inhibitor of phosphofructokinase

Question 5

Which of the following substances is NOT a product of glycolysis?

Accepted Answer

FADH2

Answer

Pyruvate

Answer

ATP

Answer

NADH

Question 6

What is the main purpose of the preparatory phase of glycolysis?

Accepted Answer

Convert glucose into a more reactive form

Answer

Generate pyruvate

Answer

Produce ATP

Answer

Reduce NAD+

Question 7

Which molecule serves as the initial substrate for glycolysis?

Accepted Answer

Glucose

Answer

Acetyl-CoA

Answer

Pyruvate

Answer

Citric acid

Question 8

Which enzyme catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate in glycolysis?

Accepted Answer

Glucose-6-phosphate isomerase

Answer

Hexokinase

Answer

Fructokinase

Answer

Phosphofructokinase

Question 9

Which molecule is the primary product of glycolysis in the presence of oxygen?

Accepted Answer

Pyruvate

Answer

Acetyl-CoA

Answer

NADH

Answer

ATP

Question 10

What is the primary role of NAD+ in glycolysis?

Accepted Answer

Acceptor of electrons

Answer

Donor of electrons

Answer

Cofactor for enzymes

Answer

Substrate for enzymes

Question 11

What is the primary consequence of inhibiting hexokinase?

Accepted Answer

Blocked entry of glucose into glycolysis

Answer

Increased production of pyruvate

Answer

Decreased levels of NADH

Answer

Reduced formation of acetyl-CoA

Question 12

Which hormone is known to stimulate glycolysis?

Accepted Answer

Epinephrine

Answer

Insulin

Answer

Glucagon

Answer

Progesterone

Question 13

How does glycolysis contribute to ATP production when oxygen is not available?

Accepted Answer

Through substrate-level phosphorylation

Answer

Via oxidative phosphorylation

Answer

By generating electron carriers

Answer

It does not contribute to ATP production under anaerobic conditions

Question 14

What is the net gain of ATP molecules produced during glycolysis?

Accepted Answer

2

Answer

1

Answer

4

Answer

6

Question 15

Which of the following is a substrate used in glycolysis?

Accepted Answer

Glucose

Answer

Fructose-1,6-bisphosphate

Answer

Acetyl CoA

Answer

Oxaloacetate

Question 16

Which type of bond is formed during the dehydration step of glycolysis?

Accepted Answer

Ester bond

Answer

Glycosidic bond

Answer

Phosphodiester bond

Answer

Peptide bond

Question 17

What is the function of glyceraldehyde-3-phosphate dehydrogenase in glycolysis?

Accepted Answer

To oxidize glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate

Answer

To reduce glyceraldehyde-3-phosphate to glyceraldehyde-3-phosphate dehydrogenase

Answer

To isomerize glyceraldehyde-3-phosphate to dihydroxyacetone phosphate

Answer

To phosphorylate glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate

Question 18

Which of the following is a product of the substrate-level phosphorylation step in glycolysis?

Accepted Answer

ATP

Answer

ADP

Answer

NADH

Answer

FADH2

Question 19

Which of the following does NOT occur during the conversion of phosphoenolpyruvate to pyruvate?

Accepted Answer

NADH is produced

Answer

A water molecule is removed

Answer

A phosphate group is removed

Answer

ATP is generated

Question 20

What is the overall goal of glycolysis?

Accepted Answer

To break down glucose into pyruvate and generate energy in the form of ATP and NADH

Answer

To produce ATP and NADH

Answer

To generate reducing equivalents

Answer

To convert glucose into carbon dioxide

Question 21

Which enzyme catalyzes the irreversible step in glycolysis, converting 1,3-bisphosphoglycerate to 3-phosphoglycerate?

Accepted Answer

Phosphoglycerate kinase

Answer

Phosphohexose isomerase

Answer

Aldolase

Answer

Glyceraldehyde-3-phosphate dehydrogenase

Question 22

What is the net gain of ATP molecules during glycolysis per molecule of glucose?

Accepted Answer

2

Answer

8

Answer

6

Answer

4

Question 23

Under anaerobic conditions, which molecule is produced as a byproduct of glycolysis, facilitating the regeneration of NAD+?

Accepted Answer

Lactate

Answer

Acetyl-CoA

Answer

Pyruvate

Answer

Carbon dioxide

Question 24

What is the primary role of hexokinase in glycolysis?

Accepted Answer

To phosphorylate glucose, trapping it inside the cell and initiating the glycolytic pathway

Answer

To generate ATP from ADP

Answer

To convert glucose-6-phosphate to fructose-6-phosphate

Question 25

Which reaction in glycolysis involves the oxidation of glyceraldehyde-3-phosphate, resulting in the generation of NADH?

Accepted Answer

Glyceraldehyde-3-phosphate dehydrogenase

Answer

Triose phosphate isomerase

Answer

Enloase

Answer

Phosphoglycerate mutase

Question 26

What is the purpose of the preparatory phase of glycolysis, occurring in the first five steps?

Accepted Answer

To convert glucose into two molecules of glyceraldehyde-3-phosphate, preparing it for further energy extraction

Answer

To produce ATP and NADH

Answer

To generate pyruvate

Question 27

What is the final product of glycolysis, marking the completion of the glucose breakdown pathway?

Accepted Answer

Pyruvate

Answer

Citrate

Answer

Acetyl-CoA

Answer

Lactate

Question 28

Which enzyme is responsible for the cleavage of fructose-1,6-bisphosphate in glycolysis, leading to the formation of two triose phosphates?

Accepted Answer

Aldolase

Answer

Phosphoglycerate kinase

Answer

Triose phosphate isomerase

Answer

Glyceraldehyde-3-phosphate dehydrogenase